Driving is the only way into Gonzales. US Highway 183 runs north to south through the city, while US Highway 90 runs east to west. From Austin, take US Hwy 183 due south for about an hour. From San Antonio, follow I-10 east to exit 632US 183 to Gonzales/Cuero, and drive south on 183 for 15 miles to reach Gonzales. From Houston, follow I-10 west to exit 632, and drive south.
